Tom Colace is always thinking of process solutions, even when he’s relaxing smoking meats. Whether he’s optimizing extrahepatic delivery of therapeutic mRNA or patiently infusing sweet smoke from cherry wood into a brisket, his PhD. in chemical engineering and molecular biology from The University of Pennsylvania and his B.S. degree in chemical engineering from Northwestern University is ingrained on how he puzzles through challenges methodically. Before his leadership role at Kernal, Tom has been part of large pharma (Merck, Pharmaceutical Science division) working on specialized projects. But as an innate problem-solver, he learned that he thrived as a generalist in a start-up culture at Verve. There, Tom developed LNP formulations to deliver base editor mRNA to the liver, and scaled up LNP manufacturing process to support IND-enabling studies.