selective
TRANSLATION

activation activation on activation off

OUR mRNA SELECTIVELY BOOSTS CANCER-FIGHTING PROTEINS IN THE DISEASED WHILE MINIMIZING OFF-TARGET TOXICITY IN THE HEALTHY:

diseased healthy

precision
TARGETING

delivery

MOST LNP-DELIVERED mRNA DEFAULTS TO THE LIVER. OURS REACH THE RIGHT TISSUE AND THE RIGHT CELL:

tumor cell-specific LNP-encased mRNA immune cell-specific LNP-encased mRNA
body diagram

This is mRNA 2.0. Elegantly designed. Selectively translated.

decode

Decode.

We mine massive multi-dimensional datasets to identify targetable nuances in the genetic code unique to different cell types. Malignant vs non-maglinant. Immune cells vs liver cells.

design

Design.

We insert these signatures into the designer mRNA to target specific cells. Hyperselective translation activates malignant cells to make cancer-fighting proteins. Other cells can be activated to make health-promoting ones.

deliver

Deliver.

We control the engineered mRNA’s journey into specific cells within target tissue using proprietary and versatile LNPs. By evading default accumulation in the liver, we can reach diverse tissues, such as tumor, spleen, and bone marrow.