hyperselective
ACTIVATION

activation activation on activation off

LIKE AN ON-OFF SWITCH, DESIGNER mRNA INSTRUCTS SPECIFIC CELLS TO MAKE SPECIFIC PROTEINS THAT PROMOTE HEALING ( I ) OR SUPPRESS DISEASE ( O ):

promtion supression

versatile
DELIVERY

delivery

MOST LNP-DELIVERED mRNA DEFAULTS TO THE LIVER. OURS REACH THE RIGHT TISSUE AND THE RIGHT CELL:

brain tumor lung
body diagram

This is mRNA 2.0. Elegantly designed. Selectively activated.

decode

Decode.

We mine massive multi-dimensional datasets to identify targetable nuances in the genetic code unique to different cell types. Brain vs lung. Malignant vs non-maglinant. Epithelial vs endothelial.

design

Design.

We insert these signatures into the designer mRNA to target specific cells. Hyperselective translation activates malignant cells to make cancer-fighting proteins. Other cells can be activated to make health-promoting ones.

deliver

Deliver.

We control the designer mRNA’s journey into specific cells within target tissue using proprietary lipid nanoparticles that evade default accumulation in the liver.