Isaak’s first exposure to the RNA world was during his master thesis in Yaakov Benenson’s group at ETH Zurich, testing the functionality of trans-cleaving Hammerhead ribozymes in mammalian cells. He then moved to Cambridge for his Ph.D. in Timothy Lu’s lab at MIT where he worked on developing tools for engineering probiotic microbes for therapeutic and diagnostic purposes. After a two-year post-doc in biomaterials formation in yeast and bacteria at Lawrence Berkeley National Lab with Yasuo Yoshikuni, Isaak’s career came “full circle” with his move back to Cambridge to join Kernal Bio. He is now excited to be part of the synthetic biology team advancing screening of RNA sequences and pushing the limits of onco-selective mRNA therapeutics. Outside of work, Isaak likes to spend time with his two cats Jack and Bean, cooking, hiking or watching Bundesliga on the weekends.